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Table 7 Number of total, correct, and unnecessary referrals and KRT cases missed when using ≥ 5% 5-year predicted KRT risk or ACR ≥ 70 mg/mmol as referral criteria for models 2–6, compared to previous NICE guidelines (referral if eGFR < 30 ml/min/1.73 \({m}^{2}\) and/or ACR ≥ 70 mg/mmol)

From: Using the kidney failure risk equation to predict end-stage kidney disease in CKD patients of South Asian ethnicity: an external validation study

 

Correct referrals

Unnecessary referrals

Missed KRT cases

Total referrals

White (N = 11,596)

NICE guidelines

26 (4.09)

609 (96.0)

32 (55.2)

635

Model 2

29 (5.38)

510 (94.6)

29 (50.0)

539

Model 3

29 (5.50)

498 (94.5)

29 (50.0)

527

Model 4

29 (5.39)

509 (94.6)

29 (50.0)

538

Model 5

29 (7.63)

351 (92.4)

29 (50.0)

380

Model 6

30 (8.09)

341 (91.9)

28 (48.3)

371

South Asian (N = 2124)

NICE guidelines

19 (13.0)

127 (87.0)

5 (20.8)

146

Model 2

23 (10.9)

188 (89.1)

1 (4.17)

211

Model 3

23 (10.2)

202 (89.8)

1 (4.17)

225

Model 4

23 (11.0)

186 (89.0)

1 (4.17)

209

Model 5

23 (12.9)

155 (87.1)

1 (4.17)

178

Model 6

23 (12.0)

168 (88.0)

1 (4.17)

191

Overall (N = 13,720)

NICE guidelines

45 (5.76)

736 (94.0)

37 (45.1)

781

Model 2

52 (6.93)

698 (93.1)

30 (36.6)

750

Model 3

52 (6.91)

700 (93.1)

30 (36.6)

752

Model 4

52 (6.96)

695 (93.0)

30 (36.6)

747

Model 5

52 (9.32)

506 (90.7)

30 (36.6)

558

Model 6

53 (9.43)

509 (90.6)

29 (35.4)

562

  1. Values given as number (percentage of total referrals) for correct and unnecessary referrals. Values given as number (percentage of total KRT cases within 5 years) for the missed KRT cases. Models 2a, 2b and 3a, 3b have been combined when giving an assessment of the whole cohort. The eligibility assessment cohort was used, i.e. those who are not previously known to secondary care. NICE National Institute for Clinical Excellence, KRT kidney replacement therapy